Featured publication: zebrafish habenula in action


Featured Publication: TrkB hyperactivity contributes to aberrant brain connectivity development in TSC
2026
Dogra S., and Zmorzynska J. Microinjection of Interleukin-6 into the Bloodstream of TSC Zebrafish Larvae to Study Neuropsychiatric Disorder-Like Behaviors. Journal of Video Experiments (JoVE), 2026.
Nebojsa Andric, Robert N. Kelsh, Svetlana Fa Nedeljkovic, Kristina Pogrmic-Majkic, Daniëlle Copmans, Annelii Ny, Lyudmila Nikolova, Máté Varga, Breandán Kennedy, Matthias Carl, Melissa Marie Formosa, Katerina Goracinova, Justyna Zmorzynska, Alin Stelian Ciobica, Aleksandra Divac Rankov, Bojana Žegura, Marta Sendra, Matjaž Novak, Antonio Figueras, Beatriz Novoa García, Laia Ribas, Stefan H. Fuss, Diane Fatkin, Kirsten C. Sadler Edepli, Hacer Akgül Ceyhun, Robyn L. Tanguay, Murilo Sander de Abreu, Allan V. Kalueff, Saltuk Buğrahan Ceyhun. Global Landscape of Zebrafish Research (2000–2025): A Bibliometric Analysis of Publication Trends, Collaboration, and Thematic Evolution. Zebrafish, 2026. https://doi.org/10.1177/15458547261448804
2025
Z. Sas, M. Zakrzewski, W. Czestkowski, P. Wanat, A. Wardak, J. Zmorzynska, A. Marusiak and R. Serwa, Minimal-tag polyamines for in situ probing of their intracellular distribution. Chem. Commun., 2026, Advance online publication. DOI: 10.1039/D5CC06304C.
T. Dulski*, S. Tolak*, J. Zmorzyńska, Challenges and hopes for treatment of anxiety disorder in the autistic population, Brain Research (2025), https://doi.org/10.1016/j.brainres.2025.149675. *equal contribution
Maciag, M., Doszyn, O., Wnorowski, A., Zmorzynska, J., & Budzynska, B. (2025). Exploring the impact of MDMA and oxytocin ligands on anxiety and social responses: A comprehensive behavioural and molecular study in the zebrafish model. Journal of psychopharmacology (Oxford, England), 2698811251324596.
Doszyn, O., Dulski, T., & Zmorzynska, J. (2025). Protocol for microinjection of rapamycin into the zebrafish habenula. STAR protocols, 6(1), 103566. Advance online publication. https://doi.org/10.1016/j.xpro.2024.103566
Doszyn, O., Dulski, T., & Zmorzynska, J. (2025). Protocol for the visualization of pRps6-positive cells in larval zebrafish brains using whole-mount immunofluorescence and light-sheet microscopy. STAR protocols, 6(1), 103587. Advance online publication. https://doi.org/10.1016/j.xpro.2024.103587
2024
Doszyn, O., Kedra, M., & Zmorzynska, J. (2024). Hyperactive mTORC1 disrupts habenula function and light preference in zebrafish model of Tuberous sclerosis complex. iScience, 27(6), 110149. https://doi.org/10.1016/j.isci.2024.110149
Doszyn, O.*, Dulski, T.*, & Zmorzynska, J. (2024). Diving into the zebrafish brain: exploring neuroscience frontiers with genetic tools, imaging techniques, and behavioral insights. Frontiers in Molecular Neuroscience, 17. 10.3389/fnmol.2024.1358844 (*equal contribution)
2023
O Doszyn, T Dulski, J Zmorzynska. The zebrafish model of Tuberous Sclerosis Complex to study epilepsy in the Handbook of Animal Models in Neurological Disease edited by Colin Martin, Vinood B Patel and Victor R Preedy, Elsevier, 2023.
2022
Olga Doszyn, Magdalena Kedra, Justyna Zmorzynska. mTORC1 hyperactivation causes sensory integration deficits due to habenula impairment. doi.org/10.1101/2022.07.20.500762, biorxiv, 2022.
2021
MT Prentzell*, U Rehbein*, MC Sandoval*, A De Meulemeester*, R Baumeister, L Brohée, B Berdel, M Bockwoldt, B Carroll, SR Chowdhury, A von Deimling, C Demetriades, G Figlia, Genomics England Research Consortium, M Eca, G de Araujo, AM Heberle, I Heiland, B Holzwarth, LA Huber, J Jaworski, M Kedra, K Kern, A Kopach, VI Korolchuk, I van ‘t Land-Kuper, M Macias, M Nellist, W Palm, S Pusch, JM Ramos Pitto, M Reil, A Reintjes, F Reuter, JR Sampson, C Scheldeman, A Siekierska, E Stefan, A Teleman, LE Thomas, O Torres-Quesada, S Trump, HD West, P de Witte, S Woltering, T Yordanov, J Zmorzynska, CA Opitz, K Thedieck. The G3BP proteins tether the TSC complex to lysosomes and suppress mTORC1 signaling. Cell, 2021, Feb 4; 184(3):655-674. (*equal contribution).
2020
M Kedra, K Kisielewska, K Banasiak, L Wolinska-Niziol, J Jaworski, J Zmorzynska. TrkB hyperactivity contributes to brain dysconnectivity, epileptogenesis, and anxiety in a zebrafish model of Tuberous Sclerosis Complex. Proc Natl Acad Sci (PNAS). 2020 Jan 28;117(4):2170-2179.
